Cancer Terms

18F SPA-RQ

Cancer Terms -> Drugs and Chemicals -> Pharmacologic Substance -> Radiopharmaceutical Compound -> Radioconjugate -> 18F SPA-RQ

18F SPA-RQ Definition

A radioconjugate consisting of the positron emitting radioisotope fluorine F 18 conjugated to the substance P antagonist receptor quantifier (SPA-RQ) used in radioimaging. [18F]-labeled substance P antagonist receptor quantifier is an antagonist of the neurokinin 1 (substance P) receptor (NK1R) and can function as a positron emission tomography (PET) imaging agent for detecting NK1R-expressing cells and tissues. NK1Rs are frequently expressed on the plasma membranes of tumor cells from glioblastoma and breast and pancreatic carcinomas.

18F SPA-RQ Synonyms

[18F]-labeled Substance P Antagonist Receptor Quantifier, [18F]SPA-RQ

Terms in 18F SPA-RQ category



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