ABCB1-C Allele
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ABCB1-C Allele Definition
Human ABCB1-C allele is the wild-type form of the human ATP-binding cassette, sub-family B (MDR/TAP), member 1 (ABCB1) gene (ABC gene family), located at located at 7q21.1, which encodes multidrug resistance protein 1. Amplification of the ABCB1 gene is a major determinant in the development of multi-drug resistance which decreases the effectiveness of many chemotherapeutic agents used in cancer treatment.
ABCB1-C Allele Synonyms
ABCB1 1 Allele, ABCB1-C, ABCB1-C Allele, MDR1-C, MDR1-C Allele, P-Glycoprotein Transporter C Allele
Terms in ABCB1-C Allele category
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