Cancer Terms

APS Protein

Cancer Terms -> Gene Product -> Protein -> Protein Organized by Function -> Signaling Protein -> Adaptor Signaling Protein -> APS Protein

APS Protein Definition

Encoded by human APS Gene, 85 kD APS Protein appears to be found in spleen, prostate, testis, uterus, small intestine, skeletal muscle, and peripheral blood leukocytes. The 632-amino acid adaptor protein contains a PH domain, a SH2 domain, and a C-terminal tyrosine phosphorylation site. APS is structurally similar to the T-cell adaptor protein/signal transducer LNK and is tyrosine-phosphorylated after BCR cross-linking. APS associates with SHC regardless of BCR stimulation and with GRB2 after BCR stimulation. (OMIM and NCI)

APS Protein Synonyms

APS Protein, APS, Adaptor Protein Containing PH and SH2 Domains, Adaptor Protein with Pleckstrin Homology and SRC Homology 2 Domains

Terms in APS Protein category



Copyright © Cancer Terms 2014 All rights reserved. | Terms of Use | Low Carb Foods

No reproduction or republication permitted.