Allogeneic Epstein-Barr Virus-Specific Cytotoxic T Lymphocytes
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Allogeneic Epstein-Barr Virus-Specific Cytotoxic T Lymphocytes Definition
A preparation of allogeneic Epstein-Barr virus (EBV) specific cytotoxic T-lymphocytes (CTL) with potential antineoplastic activity. The administration of EBV-specific CTLs, harvested from a donor with an EBV-positive tumor, into a patient exerts a CTL response against the EBV-positive cells. This results in cell lysis and inhibition of cancer cell proliferation. The Epstein-Barr virus, a ubiquitous human herpes virus, is associated with various malignancies, including nasopharyngeal carcinoma, Hodgkin's disease, non-Hodgkin's lymphoma, and other lymphomas.
Allogeneic Epstein-Barr Virus-Specific Cytotoxic T Lymphocytes Synonyms
Allogeneic Epstein-Barr Virus-Specific Cytotoxic T-Lymphocytes, Allogeneic EBV-Specific CTL
Terms in Allogeneic Epstein-Barr Virus-Specific Cytotoxic T Lymphocytes category
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