Anhydrous Tacrolimus
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Anhydrous Tacrolimus Definition
Anhydrous from of tacrolimus, a macrolide isolated from Streptomyces tsukubaensis. Tacrolimus binds to the FKBP-12 protein and forms a complex with calcium-dependent proteins, thereby inhibiting calcineurin phosphatase activity and resulting in decreased cytokine production. This agent exhibits potent immunosuppressive activity in vivo and prevents the activation of T-lymphocytes in response to antigenic or mitogenic stimulation. Tacrolimus possesses similar immunosuppressive properties to cyclosporine, but is more potent.
Anhydrous Tacrolimus Synonyms
Anhydrous Tacrolimus, ANHYDROUS TACROLIMUS
Terms in Anhydrous Tacrolimus category
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