Anisindione
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Anisindione Definition
A synthetic indanedione anticoagulant. Anisindione interferes with the vitamin K-dependent hepatic synthesis of active clotting factors by inhibiting the reduction of vitamin K. This leads to an inhibition of gamma-carboxylation of glutamic acid residues to gamma-carboxyglutamic acid in clotting factors II, VII, IX and X. The consequential effects of this inhibition include a reduced activity of these clotting factors and prolonged blood clotting time.
Anisindione Synonyms
Anisindione, 1,3-Indandione, 2-(p-methoxyphenyl)-, 2-p-Anisyl-1,3-indandione, ANISINDIONE, Miradon, Unidone
Terms in Anisindione category
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