Anti-CD3 x anti-HER-2-neu Bispecific Monoclonal Antibody
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Bispecific Antibody -> Anti-CD3 x anti-HER-2-neu Bispecific Monoclonal Antibody
Anti-CD3 x anti-HER-2-neu Bispecific Monoclonal Antibody Definition
A murine monoclonal antibody with two antigen-recognition sites: one for CD3, an antigen expressed on mature T cells, and one for HER-2-neu, a tumor-associated antigen that promotes tumor growth. Ertumaxomab attaches to CD3-expressing T cells and HER-2-neu-expressing tumor cells, selectively cross-linking tumor and immunologic cells which results in the recruitment of cytotoxic T cells to the T cell/tumor cell aggregate.
Anti-CD3 x anti-HER-2-neu Bispecific Monoclonal Antibody Synonyms
Ertumaxomab, Anti-CD3 x anti-HER-2-neu Bispecific Monoclonal Antibody
Terms in Anti-CD3 x anti-HER-2-neu Bispecific Monoclonal Antibody category
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