Cancer Terms

Anti-Endosialin Monoclonal Antibody MORAb-004

Cancer Terms -> Drugs and Chemicals -> Pharmacologic Substance -> Biological Agent -> Monoclonal Antibody -> Anti-Endosialin Monoclonal Antibody MORAb-004

Anti-Endosialin Monoclonal Antibody MORAb-004 Definition

A humanized IgG1 monoclonal antibody directed against human endosialin/TEM1 (tumor endothelial marker;CD248) with potential anti-angiogenic and antineoplastic activities. Anti-endosialin/TEM1 monoclonal antibody MORAb-004 binds to and inhibits the activity of cell surface protein endosialin/TEM1, which may result in the inhibition of angiogenesis, tumor cell proliferation and metastasis. Endosialin/TEM1 plays a key role in angiogenesis and may be overexpressed on tumor stromal cells and endothelial cells.

Anti-Endosialin Monoclonal Antibody MORAb-004 Synonyms

Anti-Endosialin Monoclonal Antibody MORAb-004, MORAb-004

Terms in Anti-Endosialin Monoclonal Antibody MORAb-004 category



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