Cancer Terms

Anti-Mesothelin Monoclonal Antibody

Cancer Terms -> Drugs and Chemicals -> Pharmacologic Substance -> Biological Agent -> Monoclonal Antibody -> Anti-Mesothelin Monoclonal Antibody

Anti-Mesothelin Monoclonal Antibody Definition

A humanized IgG1 monoclonal antibody against human mesothelin with potential anti-tumor activity. Anti-mesothelin monoclonal antibody specifically targets mesothelin, a cell surface glycoprotein involved in cell adhesion and overexpressed on many epithelial-derived cancer cells. Upon binding to the mesothelin antigen, anti-mesothelin monoclonal antibody triggers an antibody dependent cellular cytotoxicity (ADCC)-mediated host immune response against mesothelin-expressing cells, resulting in cell lysis.

Anti-Mesothelin Monoclonal Antibody Synonyms

Anti-Mesothelin Monoclonal Antibody MORAb-009, MORAb-009

Terms in Anti-Mesothelin Monoclonal Antibody category



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