Antineoplaston A10
Cancer Terms ->
Drugs and Chemicals ->
Pharmacologic Substance ->
Antineoplastic Agent ->
Cell Differentiating Agent ->
Differentiation Inducer ->
Antineoplaston Agent -> Antineoplaston A10
Antineoplaston A10 Definition
A piperidinedione antineoplaston with potential antineoplastic activity. Antineoplaston A10 was originally isolated from human urine but is now synthetically derived. This agent intercalates into DNA, resulting in cell cycle arrest in G1 phase, reduction of mitosis, and decreased protein synthesis. Antineoplaston A10 may also inhibit ras-oncogene expression and activate tumor suppressor gene p53, leading to cell differentiation and apoptosis. (NCI04)
Antineoplaston A10 Synonyms
Antineoplaston A10, 3-Phenylacetylamino-2, 6-piperidinedione, 3-Phenylacetylamino-2,6-piperidinedione
Terms in Antineoplaston A10 category
Copyright © Cancer Terms 2014 All rights reserved. | Terms of Use | Low Carb Foods
No reproduction or republication permitted.