Cancer Terms

Antineoplaston AS2-1

Cancer Terms -> Drugs and Chemicals -> Pharmacologic Substance -> Antineoplastic Agent -> Cell Differentiating Agent -> Differentiation Inducer -> Antineoplaston Agent -> Antineoplaston AS2-1

Antineoplaston AS2-1 Definition

A 4:1 mixture of phenylacetate and phenylacetylgluatmine, degradation products of the antineoplaston agent A10. Antineoplaston AS2-1 inhibits the incorporation of L-glutamine into tumor-cell proteins, leading to cell cycle arrest in the G1 phase and inhibition of mitosis. This agent may also inhibit RAS oncogene expression and activate tumor suppressor gene p53, resulting in cell differentiation and apoptosis. (NCI04)

Antineoplaston AS2-1 Synonyms

Antineoplaston AS2-1

Terms in Antineoplaston AS2-1 category



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