Cancer Terms

Arzoxifene Hydrochloride

Cancer Terms -> Drugs and Chemicals -> Pharmacologic Substance -> Chemopreventive Agent -> Selective Estrogen Receptor Modulator -> Arzoxifene Hydrochloride

Arzoxifene Hydrochloride Definition

The hydrochloride salt of arzoxifene, a synthetic aromatic derivative with anti-estrogenic properties. Arzoxifene binds to estrogen receptors as a mixed estrogen agonist/antagonist. In comparison to other selective estrogen receptor modulators (SERMs), arzoxifene exhibits greater bioavailability and higher anti-estrogenic potency in the breast than raloxifene; it exhibits reduced estrogenicity in the uterus compared with either tamoxifen or raloxifene. This agent may have beneficial effects on bone and the cardiovascular system.

Arzoxifene Hydrochloride Synonyms

Arzoxifene Hydrochloride, 2-(4-Methoxyphenyl)-3-[4-[2-(1-piperidinyl)ethoxy]phenoxy]benzo[b]thiophene-6-ol hydrochloride, Arzoxifene.HCl, Arzoxifenehydrochloride, LY353381 Hydrochloride, LY353381 hydrochloride, LY353381.HCl, SERM-3, SERM3

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