Atrasentan
Cancer Terms ->
Drugs and Chemicals ->
Pharmacologic Substance ->
Endothelin Receptor Antagonist ->
Endothelin-1 Protein Receptor Antagonist -> Atrasentan
Atrasentan Definition
The orally available hydrochloride salt of pyrrolidine-3-carboxylic acid with potential antineoplastic activity. As a selective antagonist of the endothelin-A (ETA) receptor, atrasentan binds selectively to the ETA receptor, which may result in inhibition of endothelin-induced angiogenesis and tumor cell proliferation.
Atrasentan Synonyms
Atrasentan Hydrochloride, (+)-A 127722, (2R,3R,4S)-4-(1,3-Benzodioxo-5-yl)-1-(2-(dibutylamino)-2-oxoethyl)-2-(4-methoxyphenyl)-3-pyrrolidinecarboxylic Acid Monohydrochloride, ABT-627, ATRASENTAN HYDROCHLORIDE, Xinlay
Terms in Atrasentan category
Copyright © Cancer Terms 2014 All rights reserved. | Terms of Use | Low Carb Foods
No reproduction or republication permitted.