Cancer Terms

Azelastine Hydrochloride

Cancer Terms -> Drugs and Chemicals -> Pharmacologic Substance -> Biological Response Modifier -> Histamine-1 Receptor Antagonist -> Azelastine Hydrochloride

Azelastine Hydrochloride Definition

The hydrochloride salt form of azelastine, a phthalazinone derivative with antihistaminergic activity. Azelastine hydrochloride competes with histamine for the H1 receptor, thereby diminishing the actions of histamine on effector cells and decreasing the histamine-mediated symptoms of allergic reaction, such as bronchoconstriction, vasodilation, increased capillary permeability and spasmodic contractions of gastrointestinal smooth muscle.

Azelastine Hydrochloride Synonyms

Azelastine Hydrochloride, 1(2H)-Phthalazinone, 4-((4-Chlorophenyl)methyl)-2-(hexahydro-1-methyl-1H-azepin-4-yl)-, Monohydrochloride, AZELASTINE HYDROCHLORIDE, Astelin, Optivar, W-2979M

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