BAY 43-9006
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BAY 43-9006 Definition
The tosylate salt of sorafenib, a synthetic compound targeting growth signaling and angiogenesis. Sorafenib blocks the enzyme RAF kinase, a critical component of the RAF/MEK/ERK signaling pathway that controls cell division and proliferation; in addition, sorafenib inhibits the VEGFR-2/PDGFR-beta signaling cascade, thereby blocking tumor angiogenesis.
BAY 43-9006 Synonyms
Sorafenib Tosylate, 4-(4-(3-(4-Chloro-3-trifluoromethylphenyl)ureido)phenoxy)pyridine-2-carboxyllic Acid Methyamide-4-methylbenzenesulfonate Tosylate, BAY 43-9006 Tosylate, BAY 54-9085, Nexavar, SORAFENIB TOSYLATE
Terms in BAY 43-9006 category
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