Cancer Terms

BCR Protein

Cancer Terms -> Gene Product -> Protein -> Protein Organized by Function -> Signaling Protein -> GTPase-Activating Protein -> BCR Protein

BCR Protein Definition

The 160 kD BCR phosphoprotein exhibits a unique serine/threonine kinase activity, at least two SH2 binding sites, and a C-terminal GTPase activating domain for p21(rac). The Philadelphia translocation produces a BCR-ABL1 chimeric product required for induction and maintenance of leukemia. (from OMIM 151410 and NCI)

BCR Protein Synonyms

BCR Protein, ALL, BCR, BCR1, Breakpoint Cluster Region Protein, CML, D22S11, D22S662, PHL

Terms in BCR Protein category



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