BCR-ABL Oncoprotein
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BCR-ABL Oncoprotein Definition
An onco-protein generated from the fusion of Bcr and Abl genes by translocation process between chromosome 9 and 22 (Philadelphia chromosome), in CML (P210) and some ALL (P190). Aberrant expression of BCR-ABL in bone marrow cells results in a variety of leukemias.
BCR-ABL Oncoprotein Synonyms
BCR-ABL Oncoprotein, BCR ABL Fusion Protein, BCR-ABL Protein Tyrosine Kinase, BCR/ABL
Terms in BCR-ABL Oncoprotein category
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