BRCA2 Mutation

Cancer Terms -> Molecular Abnormality -> Molecular Genetic Abnormality -> Gene Abnormality -> BRCA2 Mutation

BRCA2 Mutation Definition

A mutation that is typically a heritable, permanent change in the nucleotide sequence of the BRCA2 gene. Single nucleotide substitutions and small deletions or insertions (1-20 bases) account for the majority of mutations in the BRCA2 gene. Most of these alterations result in a truncated form of the breast cancer type 2 susceptibility protein. Mutations in the BRCA2 gene predispose males to breast cancer.

BRCA2 Mutation Synonyms

BRCA2 Mutation, Mutation of the BRCA2 Gene

Terms in BRCA2 Mutation category

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