Beta Catenin

Cancer Terms -> Gene Product -> Protein -> Protein Organized by Function -> Signaling Protein -> Beta Catenin

Beta Catenin Definition

Beta-catenin is an adherens junction protein. Adherens junctions (AJs; also called the zonula adherens) are critical for the establishment and maintenance of epithelial layers, such as those lining organ surfaces. AJs mediate adhesion between cells, communicate a signal that neighboring cells are present, and anchor the actin cytoskeleton. In serving these roles, AJs regulate normal cell growth and behavior. At several stages of embryogenesis, wound healing, and tumor cell metastasis, cells form and leave epithelia. This process, which involves the disruption and reestablishment of epithelial cell-cell contacts, may be regulated by the disassembly and assembly of AJs. AJs may also function in the transmission of the contact inhibition' signal, which instructs cells to stop dividing once an epithelial sheet is complete. (from OMIM)

Beta Catenin Synonyms

Beta Catenin, Beta-Catenin, CTNNB1, CUL-2, Cadherin-Associated Protein, Beta, Cadherin-Associated Protein, Beta 1 (88kD), Catenin, Beta-1, Cullin 2 Protein, Cullin Homolog 2, PRO2286

Beta Catenin

Beta Catenin Definition

Beta Catenin Synonyms

Terms in Beta Catenin category