Cancer Terms

Biricodar Dicitrate

Cancer Terms -> Drugs and Chemicals -> Pharmacologic Substance -> Multidrug Resistance Modulator -> Biricodar Dicitrate

Biricodar Dicitrate Definition

The dicitrate salt of a synthetic pipecolinate derivative with potential chemosensitizing activity. Biricodar binds directly to the plasma membrane drug-efflux pumps P-glycoprotein (P-gp) and multidrug resistance protein 1 (MRP-1) and inhibits their activities, which may result in increased intracellular accumulation and retention of cytotoxic agents.

Biricodar Dicitrate Synonyms

Biricodar Dicitrate, BIRICODAR DICITRATE, Incel, Incel VX-710, VX-710

Terms in Biricodar Dicitrate category



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