Cancer Terms

Borocaptate Sodium

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Borocaptate Sodium Definition

A boron-carrying compound. After parenteral administration, sodium borocaptate accumulates preferentially in tumor cells. When exposed to neutron irradiation, borocaptate absorbs neutrons and self-destructs releasing short-range alpha radiation and 'recoil' lithium in tumor cells, resulting in alpha radiation-induced tumor cell death. This highly selective, localized radiotargeting of tumor cells, known as boron neutron capture therapy (BNCT), spares adjacent normal tissues. (NCI04)

Borocaptate Sodium Synonyms

Sodium Borocaptate, BSH, Borocaptate Sodium, Borocarpin

Terms in Borocaptate Sodium category

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