Brivudine
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Brivudine Definition
A synthetic analog of the nucleoside thymidine with antiviral activity. Brivudine is selectively taken up by herpes simplex-1 (HSV-1) infected cells and undergoes phosphorylation by the viral deoxythymidine kinase to its active mono- and triphosphate forms. Once in its active form, brivudine is incorporated into the viral DNA and subsequently inhibits the actions of DNA polymerases, generating an inhibitory effect on viral replication.
Brivudine Synonyms
Brivudine, BRIVUDINE
Terms in Brivudine category
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