C-KIT wt Allele

Cancer Terms -> Gene -> Ligand Binding Protein Gene -> Receptor Gene -> Receptor Tyrosine Kinase Gene -> C-KIT Gene -> C-KIT wt Allele

C-KIT wt Allele Definition

Human KIT wild-type allele is located within 4q11-q12 and is approximately 83 kb in length. This allele, which encodes mast/stem cell growth factor receptor protein, plays a role in the mediation of transmembrane-receptor interactions. Mutations in the gene are associated with gastrointestinal stromal tumors, mast cell disease, acute myelogenous lukemia, and piebaldism.

C-KIT wt Allele Synonyms

KIT wt Allele, C-KIT, CD117, KIT, SCF Receptor Gene, SCFR, Stem Cell Factor Receptor Gene, V-Kit Hardy-Zuckerman 4 Feline Sarcoma Viral Oncogene Homolog wt Allele

Terms in C-KIT wt Allele category

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