CAAX-Farnesyltransferase Beta Subunit
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Protein Complex Subunit -> CAAX-Farnesyltransferase Beta Subunit
CAAX-Farnesyltransferase Beta Subunit Definition
Encoded by human FNTB Gene (Protein Prenyltransferase Alpha Subunit Family), 437-aa 49-kDa CAAX Box Farnesyltransferase Beta Subunit is part of 100-kD heterodimeric Farnesyl Protein Transferase, which catalyzes 15-C farnesyl thioether linkage to the C-terminal Cys in C(ys)AAX boxes of many proteins as a means of membrane localization. The FTase beta chain is catalytic for specific substrates. With both conserved alpha and beta subunits essential for catalytic activity, FNTB (5 PFTB repeats) binds the substrate; the alpha subunit may promote a stable complex with substrate. (NCI)
CAAX-Farnesyltransferase Beta Subunit Synonyms
CAAX Box Farnesyltransferase Beta Subunit, CAAX Box Farnesyltransferase Beta, FNTB, FPTB, FTase-Beta, Protein Farnesyltransferase Beta Subunit, RAS Proteins Prenyltransferase Beta
Terms in CAAX-Farnesyltransferase Beta Subunit category
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