CCND1 wt Allele

Cancer Terms -> Gene -> Cell Cycle Gene -> Cyclin Gene -> CCND1 Gene -> CCND1 wt Allele

CCND1 wt Allele Definition

Human CCND1 wild-type allele is located within 11q13 and is approximately 13 kb in length. This allele, which encodes G1/S-specific cyclin-D1 protein, plays a role in the regulation of the cell cycle during the G1/S transition. Aberrant allelic expression caused by mutations, amplification and overexpression alters cell cycle progression. These abnormal alterations have been frequently identified in a variety of tumors and may contribute to tumorigenesis.

CCND1 wt Allele Synonyms

CCND1 wt Allele, BCL1, Cyclin D1 wt Allele, D11S287E, PRAD1, U21B31

Terms in CCND1 wt Allele category

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