Cancer Terms

CHD5 wt Allele

Cancer Terms -> Gene -> Enzyme Gene -> Hydrolase Gene -> Helicase Gene -> CHD5 Gene -> CHD5 wt Allele

CHD5 wt Allele Definition

Human CHD5 wild-type allele is located in the vicinity of 1p36.3 and is approximately 78 kb in length. This allele, which encodes chromodomain-helicase-DNA-binding protein 5, is involved in chromatin remodeling and transcriptional regulation. Depletion of the wild-type allele contributes to the pathogenesis of several cancers; including: neural cancers, melanoma, hematopoietic cancers and several epithelial cancers.

CHD5 wt Allele Synonyms

CHD5 wt Allele, Chromodomain Helicase DNA Binding Protein 5 wt Allele, DKFZp434N231, KIAA0444

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