Cancer Terms

CYP1A1 wt Allele

Cancer Terms -> Gene -> Enzyme Gene -> Oxidoreductase Gene -> Cytochrome P450 Family Gene -> CYP1A1 Gene -> CYP1A1 wt Allele

CYP1A1 wt Allele Definition

Human CYP1A1 wild-type allele is located within 15q22-q24 and is approximately 6 kb in length. This allele, which encodes cytochrome P450 1A1 protein, plays a role in the metabolism of polyaromatic hydrocarbons (PAHs). Individuals with a high-inducibility phenotype, who exhibit elevated CYP1A1 gene expression in response to PAHs, may be at greater risk for cigarette smoke-induced bronchogenic carcinoma.

CYP1A1 wt Allele Synonyms

CYP1A1 wt Allele, AHH, AHRR, CP11, CY11, CYP1, Cytochrome P450, Family 1, Subfamily A, Polypeptide 1 wt Allele, P1-450, P450-C, P450DX, P450DX

Terms in CYP1A1 wt Allele category



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