Cancer Terms

CYP2C19 2 Allele

Cancer Terms -> Gene -> Enzyme Gene -> Oxidoreductase Gene -> Cytochrome P450 Family Gene -> CYP2C19 Gene -> CYP2C19 2 Allele

CYP2C19 2 Allele Definition

Human CYP2C19*2 allele is located within 10q24.1-q24.3 and is approximately 90 kb in length. This allele, a variant form of the CYP2C19 wild-type allele, encodes cytochrome P450 2C19*2 protein. The CYP2C19*2 allele exhibits a clinically-relevant SNP (c.681G>A) in exon 5 that causes a splicing defect; this alteration results in a truncated cytochrome P450 2C19*2 protein that is enzymatically inactive.

CYP2C19 2 Allele Synonyms

CYP2C19*2 Allele, CYP2C19*2, CYP2C19, c.681G>A, CYP2C19, m1, CYP2C19, m1A, CYP2C19, m1B, Cytochrome P450, Family 2, Subfamily C, Polypeptide 19*2 Allele

Terms in CYP2C19 2 Allele category



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