Cancer Terms

CYP2C8 4 Allele

Cancer Terms -> Gene -> Enzyme Gene -> Oxidoreductase Gene -> Cytochrome P450 Family Gene -> CYP2C8 Gene -> CYP2C8 4 Allele

CYP2C8 4 Allele Definition

Human CYP2C8*4 allele is located in the vicinity of 10q23.33 and is approximately 33 kb in length. This allele, a variant form of the CYP2C8 wild-type allele, encodes cytochrome P450 2C8*4 protein. The CYP2C8*4 allele exhibits a SNP (c.792C>G) in exon 5 that results in an I264M coding change. However, this alteration in protein sequence has no significant effect on the enzymatic activity of the cytochrome P450 2C8*4 protein.

CYP2C8 4 Allele Synonyms

CYP2C8*4 Allele, CYP2C8*4, CYP2C8, I264M, CYP2C8, c.792C>G, Cytochrome P450, Family 2, Subfamily C, Polypeptide 8*4 Allele

Terms in CYP2C8 4 Allele category



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