CYP2C9 12 Allele
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CYP2C9 Gene -> CYP2C9 12 Allele
CYP2C9 12 Allele Definition
Human CYP2C9*12 allele is located within 10q24 and is approximately 33 kb in length. This allele, a variant form of the CYP2C9 wild-type allele, encodes cytochrome P450 2C9*12 protein. The CYP2C9*12 allele exhibits a clinically-relevant SNP (c.1465C>T) in exon 9 that results in a P489S coding change. This alteration in protein sequence decreases the enzymatic activity of the cytochrome P450 2C9*12 protein.
CYP2C9 12 Allele Synonyms
CYP2C9*12 Allele, CYP2C9*12, CYP2C9, P489S, CYP2C9, c.1465C>T, Cytochrome P450, Family 2, Subfamily C, Polypeptide 9*12 Allele
Terms in CYP2C9 12 Allele category
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