CYP2D6 17 Allele
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CYP2D6 17 Allele Definition
Human CYP2D6*17 allele is located in the vicinity of 22q13.1 and is approximately 4 kb in length. This allele, a variant form of the CYP2D6 wild-type allele, encodes cytochrome P450 2D6*17 protein. The CYP2D6*17 allele exhibits two clinically-relevant SNPs (g.1023C>T, g.2850C>T) that result in coding changes (T107I, R296C). These alterations decrease the enzymatic activity of the cytochrome P450 2D6*17 protein.
CYP2D6 17 Allele Synonyms
CYP2D6*17 Allele, CYP2D6*17, CYP2D6, T107I, R296C, CYP2D6, g.1023C>T, g.2850C>T, CYP2D6Z, Cytochrome P450, Family 2, Subfamily D, Polypeptide 6*17 Allele
Terms in CYP2D6 17 Allele category
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