CYP2D6 2 Allele
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CYP2D6 2 Allele Definition
Human CYP2D6*2 allele is located in the vicinity of 22q13.1 and is approximately 4 kb in length. This allele, a variant form of the CYP2D6 wild-type allele, encodes cytochrome P450 2D6*2 protein. The majority of haplotypes of the CYP2D6*2 allele exhibit SNPs (g.2850C>T; g.4180G>C) in exons 6 and 9 that result in R296C and S486T coding changes. These alterations in protein sequence have no significant effect on the enzymatic activity of the cytochrome P450 2D6*2 protein.
CYP2D6 2 Allele Synonyms
CYP2D6*2 Allele, CYP2D6*2, CYP2D6, R296C, S486T, CYP2D6, g.2850C>T, g.4180G>C, CYP2D6L, Cytochrome P450, Family 2, Subfamily D, Polypeptide 6*2 Allele
Terms in CYP2D6 2 Allele category
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