Cancer Terms

CYP2D6 2N Allele

Cancer Terms -> Gene -> Enzyme Gene -> Oxidoreductase Gene -> Cytochrome P450 Family Gene -> CYP2D6 Gene -> CYP2D6 2N Allele

CYP2D6 2N Allele Definition

Human CYP2D6*2N allele, a variant form of the CYP2D6 wild-type allele, is approximately 4 kb in length and encodes cytochrome P450 2D6 protein. Amplification of the CYP2D6 gene (up to 12 copies) produces the CYP2D6*2N allele. The enzymatic activity of the protein encoded by this allele is not significantly different from the protein product of the wild-type allele. However, individuals who carry this allele exhibit an ultra-rapid metabolizer phenotype.

CYP2D6 2N Allele Synonyms

CYP2D6*2N Allele, CYP2D6*2XN, Cytochrome P450, Family 2, Subfamily D, Polypeptide 6*2N Allele

Terms in CYP2D6 2N Allele category



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