Cancer Terms

CYP2D6 42 Allele

Cancer Terms -> Gene -> Enzyme Gene -> Oxidoreductase Gene -> Cytochrome P450 Family Gene -> CYP2D6 Gene -> CYP2D6 42 Allele

CYP2D6 42 Allele Definition

Human CYP2D6*42 allele is located in the vicinity of 22q13.1 and is approximately 4 kb in length. This allele, a variant form of the CYP2D6 wild-type allele, encodes cytochrome P450 2D6*42 protein. The CYP2D6*42 allele exhibits a two nucleotide insertion (g.3259insGT) that results in a frameshift during protein coding. This alteration abolishes the enzymatic activity of the cytochrome P450 2D6*42 protein.

CYP2D6 42 Allele Synonyms

CYP2D6*42 Allele, CYP2D6*42, CYP2D6, g.3259insGT, Cytochrome P450, Family 2, Subfamily D, Polypeptide 6*42 Allele

Terms in CYP2D6 42 Allele category



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