CYP2D6 6 Allele
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CYP2D6 6 Allele Definition
Human CYP2D6*6 allele is located in the vicinity of 22q13.1 and is approximately 4 kb in length. This allele, a variant form of the CYP2D6 wild-type allele, encodes cytochrome P450 2D6*6 protein. The CYP2D6*6 allele exhibits a single nucleotide deletion (g.1707delT) in exon 3 that results in a frameshift and generates a stop codon located one codon after the deletion. This alteration yields a truncated CYP2D6*6 protein that is enzymatically inactive.
CYP2D6 6 Allele Synonyms
CYP2D6*6 Allele, CYP2D6*6, CYP2D6, g.1707delT, CYP2D6T, Cytochrome P450, Family 2, Subfamily D, Polypeptide 6*6 Allele
Terms in CYP2D6 6 Allele category
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