CYP2D6 8 Allele
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CYP2D6 8 Allele Definition
Human CYP2D6*8 allele is located in the vicinity of 22q13.1 and is approximately 4 kb in length. This allele, a variant form of the CYP2D6 wild-type allele, encodes cytochrome P450 2D6*8 protein. The CYP2D6*8 allele exhibits a clinically-relevant SNP (g.1758G>T) in exon 3 that generates a stop codon. This alteration yields a truncated cytochrome P450 2D6*8 protein that is enzymatically inactive.
CYP2D6 8 Allele Synonyms
CYP2D6*8 Allele, CYP2D6*8, CYP2D6, g.1758G>T, CYP2D6G, Cytochrome P450, Family 2, Subfamily D, Polypeptide 6*8 Allele
Terms in CYP2D6 8 Allele category
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