Cancer Terms

CYP7A1 wt Allele

Cancer Terms -> Gene -> Enzyme Gene -> Oxidoreductase Gene -> Cytochrome P450 Family Gene -> CYP7A1 Gene -> CYP7A1 wt Allele

CYP7A1 wt Allele Definition

Human CYP7A1 wild-type allele is located within 8q11-q12 and is approximately 10 kb in length. This allele, which encodes cytochrome P450 7A1 protein, plays a role in the hydroxylation of cholesterol to initiate bile acid synthesis. Functional mutations in the CYP7A1 gene that decrease or abolish the enzymatic activity of the cytochrome P450 7A1 protein are associated with elevated levels of low density lipoprotein.

CYP7A1 wt Allele Synonyms

CYP7A1 wt Allele, CP7A, CYP7, Cytochrome P450, Family 7, Subfamily A, Polypeptide 1 wt Allele

Terms in CYP7A1 wt Allele category



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