Cancer Terms

Cancer-Predisposing Gene

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Cancer-Predisposing Gene Definition

Mutated forms of genes which encode proteins that are essential for the control and maintenance of normal cellular processes. Inherited or somatic mutations in the wild-type form of these genes alters control of their expression, resulting in a change in control of the cell cycle. Individuals who harbor cancer-predisposing genes require fewer somatic mutations for transformation of a particular cell, thereby predisposing them to the development of cancer.

Cancer-Predisposing Gene Synonyms

Cancer-Predisposing Gene, Cancer Susceptibility Gene, Susceptibility Gene

Terms in Cancer-Predisposing Gene category



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