Caspase Gene
Cancer Terms -> Gene -> Enzyme Gene -> Hydrolase Gene -> Protease Gene -> Caspase Gene
Caspase Gene Definition
These genes encode caspases, a family of intracellular cysteine proteinases involved in inflammation and apoptosis. These enzymes appear to be involved in the initial signaling events, as well as the downstream proteolytic cleavages, that result in apoptotic cell death. They are specific for aspartic acid at the P1 position and are divided into two classes based on the lengths of their N-terminal pro-domains. Caspases-1, -2, -4, -5, -8, and -10 have long pro-domains while caspases-3, -6, -7, and -9 have short pro-domains. (from Science 1998. 281:1312 and Br Med Bull 1997. 53:478)Caspase Gene Synonyms
Caspase GeneTerms in Caspase Gene category
CASP10 GeneCASP1 Gene
CASP2 Gene
CASP3 Gene
CASP4 Gene
CASP5 Gene
CASP6 Gene
CASP7 Gene
CASP8 Gene
CASP9 Gene