DLC1 wt Allele

Cancer Terms -> Gene -> Regulatory Gene -> DLC1 Gene -> DLC1 wt Allele

DLC1 wt Allele Definition

Human DLC1 wild-type allele is located within 8p22 and is approximately 432 kb in length. This allele, which encodes rho-GTPase-activating protein 7 protein, is involved in cytoskeletal remodeling and negative regulation of cell growth. Loss of DLC1 gene expression due to deletion and/or hypermethylation is associated with certain types of cancer including breast cancer, hepatocellular carcinoma, gastric cancer and non-small cell lung carcinoma.

DLC1 wt Allele Synonyms

DLC1 wt Allele, ARHGAP7, Deleted in Liver Cancer 1 wt Allele, HP, STARD12

Terms in DLC1 wt Allele category

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