DNA Binding Agent

Cancer Terms -> Drugs and Chemicals -> Pharmacologic Substance -> Antineoplastic Agent -> DNA Binding Agent

DNA Binding Agent Definition

DNA binding molecules regulate mechanisms central to cellular function, including DNA replication and gene expression. Many small molecules that mimic or block these processes offer potential therapeutic agents. Understanding how complexation affects both the structural and mechanical properties of DNA is an important step towards understanding the functional mechanisms of binding agents, and may also provide a key to more rational drug design. There are three major classes of binding modes: intercalation, groove binding and covalent crosslinking.

DNA Binding Agent Synonyms

DNA Binding Agent

Terms in DNA Binding Agent category

DNA Adduct Forming Agent
DNA Crosslinking Agent
DNA Groove Binding Agent
Intercalating Agent
PM00104