Disabled Homolog-2 Protein
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Disabled Homolog-2 Protein Definition
Encoded by human tumor suppressor DAB2 Gene, Disabled Homolog 2 Protein is expressed in ovarian, breast, and lung epithelial cells, spleen, thymus, prostate, testis, macrophages, fibroblasts, placenta, brainstem, heart, and small intestine. The 770-amino acid 82.5-kD predicted protein has 83% identity with mouse p96 protein, a putative mitogen-responsive phosphoprotein; strongest homology exists in the N-terminal PTB/PID domain. Potentially phosphorylated, DAB2 is a putative component of the CSF-1 cell proliferation signal transduction pathway. (from LocusLink, Swiss-Prot, OMIM, and NCI)
Disabled Homolog-2 Protein Synonyms
Disabled Homolog 2 Protein, DAB2, DAB2 Protein, DOC-2, DOC2, Differentially Expressed Protein 2, Differentially Expressed in Ovarian Cancer 2, Disabled Homolog 2, Disabled Homolog 2, Mitogen-Responsive Phosphoprotein, Mitogen-Responsive Phosphoprotein
Terms in Disabled Homolog-2 Protein category
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