Cancer Terms

Doxylamine Succinate

Cancer Terms -> Drugs and Chemicals -> Pharmacologic Substance -> Biological Response Modifier -> Histamine-1 Receptor Antagonist -> Doxylamine Succinate

Doxylamine Succinate Definition

A pyridine derivate histamine H1 antagonist with pronounced sedative properties. Doxylamine succinate competitively blocks the histamine H1 receptor and limits the typical allergic and anaphylactic responses, including bronchoconstriction, vasodilation, increased capillary permeability, and spasmodic contraction of gastrointestinal smooth muscle, caused by actions of histamine on bronchial and gastrointestinal smooth muscles, and on capillaries. This drug also prevents histamine-induced pain and itching of the skin and mucous membranes.

Doxylamine Succinate Synonyms

Doxylamine Succinate, Butanedioic Acid, compound with N,N-dimethyl-2-[1-phenyl-1-(2-pyridinyl)ethoxy]ethanamine(1:1), DOXYLAMINE SUCCINATE, Decapryn, Dimethylaminoethoxy-methyl-benzyl-pyridine Succinate, Mereprine, N,N-dimethyl-2-[1-phenyl-1-(2-pyridinyl)ethoxy] ethanamine, butanedioate(1:1), Sedaplus, Unisom

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