EBAF wt Allele

Cancer Terms -> Gene -> Growth Factor Gene -> Transforming Growth Factor-Beta Family Gene -> EBAF Gene -> EBAF wt Allele

EBAF wt Allele Definition

Human LEFTY2 wild-type allele is located in the vicinity of 1q42.1 and is approximately 5 kb in length. This allele, which encodes transforming growth factor beta-4 protein, plays a role in the left-right asymmetry determination of organ systems during development and is also involved in endometrial bleeding regulation. Mutations in this gene produce variant alleles that are associated with left-right axis malformations, particularly in the heart and lungs. Further, certain types of infertility have been associated with aberrant allelic expression in the endometrium.

EBAF wt Allele Synonyms

LEFTY2 wt Allele, EBAF, LEFTA, LEFTYA, Left-Right Determination Factor 2 wt Allele, MGC46222, TGF-Beta 4 Gene, TGFB4

EBAF wt Allele

EBAF wt Allele Definition

EBAF wt Allele Synonyms

Terms in EBAF wt Allele category