ERBB2 wt Allele

Cancer Terms -> Gene -> Ligand Binding Protein Gene -> Receptor Gene -> Receptor Tyrosine Kinase Gene -> ERBB2 Gene -> ERBB2 wt Allele

ERBB2 wt Allele Definition

Human ERBB2 wild-type allele is located in the vicinity of 17q21.1 and is approximately 29 kb in length. This allele, which encodes receptor tyrosine-protein kinase erbB-2 protein, plays a role in EGF receptor signal transduction pathways and cellular growth. Amplification or overexpression of this gene is involved in the progression of several forms of cancer, including breast and ovarian tumors.

ERBB2 wt Allele Synonyms

ERBB2 wt Allele, ERBB2, HER2, HER2/neu, Human EGF Receptor 2 Gene, NEU Gene, NGL, TKR1, V-ERB-B2 Erythroblastic Leukemia Viral Oncogene Homolog 2, Neuro/glioblastoma Derived Oncogene Homolog (Avian) wt Allele, c-ERBB-2

ERBB2 wt Allele

ERBB2 wt Allele Definition

ERBB2 wt Allele Synonyms

Terms in ERBB2 wt Allele category