Elongation Factor-1A2
Cancer Terms ->
Gene Product ->
Protein ->
Protein Complex Subunit -> Elongation Factor-1A2
Elongation Factor-1A2 Definition
Expressed in terminally differentiated brain, heart, and skeletal muscle cells by human EEF1A2 Gene (EF-Tu/EF-1A Family), 463-aa 50-kDa Elongation Factor 1A2 is an alpha subunit of elongation factor-1 (EEF1) complex responsible for enzymatic delivery and GTP-dependent binding of aminoacyl tRNAs to the A-site of ribosomes during protein biosynthesis. EEF1A gene coding regions are highly similar; EEF1A2 exhibits 92% amino acid identity to EEF1A1. EEF1A2 has oncogenic properties: it enhances focus formation, allows anchorage-independent growth, and decreases fibroblast doubling time. EEF1A2 may be critical in development of ovarian cancer. (NCI)
Elongation Factor-1A2 Synonyms
Elongation Factor 1A2, EEF1A2, EF-1-Alpha-2, Elongation Factor 1-Alpha 2, Elongation Factor-1 Alpha, Eukaryotic Translation Elongation Factor 1 Alpha 2, Statin S1, eEF1A-2
Terms in Elongation Factor-1A2 category
Copyright © Cancer Terms 2014 All rights reserved. | Terms of Use | Low Carb Foods
No reproduction or republication permitted.