Epidermal Growth Factor Superfamily Protein

Cancer Terms -> Gene Product -> Protein -> Protein Organized by Function -> Growth Factor -> Epidermal Growth Factor Superfamily Protein

Epidermal Growth Factor Superfamily Protein Definition

Many Epidermal Growth Factor Superfamily Proteins are extracellular signaling molecules (ligands) involved in control of target cell proliferation, cell survival, and cell differentiation. The EGF superfamily is characterized by having at least 6 cysteines residues that form disulphide bonds stacked in a ladder-like arrangement, in the order 1-3, 2-4, 5-6, and which are essential for the stability of the EGF fold. Often arranged as tandem repeats in extracellular proteins, the function of the domains remains unclear, but are thought to perform a structural role.

Epidermal Growth Factor Superfamily Protein Synonyms

Epidermal Growth Factor Superfamily Protein, EGF Repeat Superfamily, Epidermal Growth Factor Repeat Superfamily

Terms in Epidermal Growth Factor Superfamily Protein category

Amphiregulin
Betacellulin
CRYPTIC Protein
Diphtheria Toxin Receptor
Epidermal Growth Factor
Epiregulin
Neuregulin