FANCM wt Allele

Cancer Terms -> Gene -> Enzyme Gene -> Hydrolase Gene -> ATPase Gene -> FANCM Gene -> FANCM wt Allele

FANCM wt Allele Definition

Human FANCM wild-type allele is located in the vicinity of 14q21.3 and is approximately 65 kb in length. This allele, which encodes Fanconi anemia group M protein, is involved in a specific protein ubiquination that is necessary for DNA repair. Cytogenetic aberrations in the FANCM gene are both a cause of Fanconi anemia and a predisposing factor in the development of malignancies.

FANCM wt Allele Synonyms

FANCM wt Allele, FAAP250, Fanconi Anemia, Complementation Group M wt Allele, KIAA1596

Terms in FANCM wt Allele category

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