FOLH1 wt Allele
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FOLH1 wt Allele Definition
Human FOLH1 wild-type allele is located in the vicinity of 11p11.2 and is approximately 62 kb in length. This allele, which encodes glutamate carboxypeptidase 2 protein, plays a role in both the uptake of folate in the intestine and the hydrolysis of N-aceylaspartylglutamate, the major neurotransmitter in the brain. This gene is overexpressed in human prostate cancer and may inhibit metastasis of this disease.
FOLH1 wt Allele Synonyms
FOLH1 wt Allele, FOLH, Folate Hydrolase (Prostate-Specific Membrane Antigen) 1 wt Allele, GCP2, NAALAD1, PSM, PSMA
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