Fexofenadine Hydrochloride
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Fexofenadine Hydrochloride Definition
The hydrochloride salt form of fexofenadine, a carboxylated metabolic derivative of terfenadine and third generation selective histamine H1-receptor antagonist with antihistaminic and non-sedative effects. Fexofenadine competitively binds peripheral H1-receptors, thereby stabilizing an inactive conformation of the receptor. Consequently histamine binding and activity as a result of mast-cell degranulation followed by the release of multiple inflammatory mediators, such as interleukins, prostaglandin and leukotriene precursors, is blocked, thereby preventing the triggering of pro-inflammatory pathways.
Fexofenadine Hydrochloride Synonyms
Fexofenadine Hydrochloride, Allegra, FEXOFENADINE HYDROCHLORIDE, Fexofenadine HCl
Terms in Fexofenadine Hydrochloride category
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